Collagen is gradually lost with aging, same as our subcutaneous fat, resulting in reduction of tension between pores, and enlargement of the pores.

Another common cause of large pore is due to repeated squeezing, which destroy the surrounding collagen.

In severe acne or skin injury, atrophic scars maybe formed when dermal collagen is damaged.

In order to reduce pores, we should rebuild the structure in dermis, by stimulating fibroblast to produce new collagen.